Cargando…
Predicting B cell receptor substitution profiles using public repertoire data
B cells develop high affinity receptors during the course of affinity maturation, a cyclic process of mutation and selection. At the end of affinity maturation, a number of cells sharing the same ancestor (i.e. in the same “clonal family”) are released from the germinal center; their amino acid freq...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205660/ https://www.ncbi.nlm.nih.gov/pubmed/30332400 http://dx.doi.org/10.1371/journal.pcbi.1006388 |