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Biological functions of 12(S)-hydroxyheptadecatrienoic acid as a ligand of leukotriene B(4) receptor 2

Although 12(S)-hydroxyheptadecatrienoic acid (12-HHT) is an abundant fatty acid, it is long considered a byproduct of thromboxane A(2) production. We identified a leukotriene B(4) receptor 2 (BLT2)-specific agonistic activity in lipid extracts from rat small intestine, and mass spectrometric analysi...

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Detalles Bibliográficos
Autores principales: Okuno, Toshiaki, Yokomizo, Takehiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205785/
https://www.ncbi.nlm.nih.gov/pubmed/30397418
http://dx.doi.org/10.1186/s41232-018-0087-4