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The fate of hippocampal synapses depends on the sequence of plasticity-inducing events

Synapses change their strength in response to specific activity patterns. This functional plasticity is assumed to be the brain’s primary mechanism for information storage. We used optogenetic stimulation of rat hippocampal slice cultures to induce long-term potentiation (LTP), long-term depression...

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Detalles Bibliográficos
Autores principales: Wiegert, J Simon, Pulin, Mauro, Gee, Christine Elizabeth, Oertner, Thomas G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205809/
https://www.ncbi.nlm.nih.gov/pubmed/30311904
http://dx.doi.org/10.7554/eLife.39151