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Thymosin α1 suppresses migration and invasion of PD-L1 high-expressing non-small-cell lung cancer cells via inhibition of STAT3–MMP2 signaling

BACKGROUND: Thymosin α1 (Tα1) is one of the most commonly used immunomodulators for metastatic non-small-cell lung cancer (NSCLC) patients in many countries. Despite the identification of the direct suppression on cancer cell proliferation, little is known about its effect on metastasis and metastas...

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Detalles Bibliográficos
Autores principales: Bo, Cong, Wu, Qiang, Zhao, Hai, Li, Xuebing, Zhou, Qinghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205819/
https://www.ncbi.nlm.nih.gov/pubmed/30425517
http://dx.doi.org/10.2147/OTT.S177943