Evidence of response to pembrolizumab in a patient with Lynch syndrome-related metastatic colon cancer

Patients with Lynch Syndrome (LS) are at high risk of developing colorectal cancer at an early age. Germline mutations in DNA mismatch repair genes and microsatellite instability are clear signatures of this autosomal dominant disorder. Here, we report the clinical history of a 38-year-old patient w...

Descripción completa

Detalles Bibliográficos
Autores principales: Salman, Pamela, Panay, Sergio, Fernández, René, Mahave, Mauricio, Soza-Ried, Cristian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205820/
https://www.ncbi.nlm.nih.gov/pubmed/30425520
http://dx.doi.org/10.2147/OTT.S167645

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205820/
https://www.ncbi.nlm.nih.gov/pubmed/30425520
http://dx.doi.org/10.2147/OTT.S167645

Ejemplares similares