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Vanadate inhibits transcription of the rat insulin receptor gene via a proximal sequence of the 5′flanking region

Vanadate, a protein tyrosine phosphatase inhibitor which elicits insulin-like effects, has previously been shown to inhibit expression of the insulin receptor gene at the transcriptional level in rat hepatoma cells. In an attempt to identify the DNA sequence and transcription factors potentially inv...

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Detalles Bibliográficos
Autores principales: Bortoli, Sylvie, Collinet, Martine, Desbuquois, Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205930/
https://www.ncbi.nlm.nih.gov/pubmed/30416963
http://dx.doi.org/10.1016/j.biopen.2018.09.001