The Nedd8-activating enzyme inhibitor MLN4924 suppresses colon cancer cell growth via triggering autophagy

Neddylation is a post-translational protein modification process. MLN4924 is a newly discovered pharmaceutical neddylation inhibitor that suppresses cancer growth with several cancer types. In our study, we first investigated the effect of MLN4924 on colon cancer cells (HCT116 and HT29). MLN4924 sig...

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Detalles Bibliográficos
Autores principales: Lv, Yongzhu, Li, Bing, Han, Kunna, Xiao, Yang, Yu, Xianjun, Ma, Yong, Jiao, Zhan, Gao, Jianjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205944/
https://www.ncbi.nlm.nih.gov/pubmed/30402022
http://dx.doi.org/10.4196/kjpp.2018.22.6.617

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205944/
https://www.ncbi.nlm.nih.gov/pubmed/30402022
http://dx.doi.org/10.4196/kjpp.2018.22.6.617

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