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Identification of Amino Acids Essential for Viral Replication in the HCMV Helicase-Primase Complex

Promising new inhibitors that target the viral helicase-primase complex have been reported to block replication of herpes simplex and varicella-zoster viruses, but they have no activity against human cytomegalovirus (HCMV), another herpesvirus. The HCMV helicase-primase complex (pUL105-pUL102-pUL70)...

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Detalles Bibliográficos
Autores principales: Ligat, Gaetan, Da Re, Sandra, Alain, Sophie, Hantz, Sébastien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205958/
https://www.ncbi.nlm.nih.gov/pubmed/30405556
http://dx.doi.org/10.3389/fmicb.2018.02483