The protective effects of maltol on cisplatin-induced nephrotoxicity through the AMPK-mediated PI3K/Akt and p53 signaling pathways

Cisplatin, a potent anticancer drug, is usually causing nephrotoxicity; limiting its therapeutic application and efficiency. Maltol may be used to prevent such toxic effect. The aim of this study was to investigate the underlying protective mechanisms of maltol on nephrotoxicity by cisplatin using a...

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Detalles Bibliográficos
Autores principales: Mi, Xiao-jie, Hou, Jin-gang, Wang, Zi, Han, Ye, Ren, Shen, Hu, Jun-nan, Chen, Chen, Li, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206039/
https://www.ncbi.nlm.nih.gov/pubmed/30374107
http://dx.doi.org/10.1038/s41598-018-34156-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206039/
https://www.ncbi.nlm.nih.gov/pubmed/30374107
http://dx.doi.org/10.1038/s41598-018-34156-6

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