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Homeostasis of protein and mRNA concentrations in growing cells

Many experiments show that the numbers of mRNA and protein are proportional to the cell volume in growing cells. However, models of stochastic gene expression often assume constant transcription rate per gene and constant translation rate per mRNA, which are incompatible with these experiments. Here...

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Detalles Bibliográficos
Autores principales: Lin, Jie, Amir, Ariel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206055/
https://www.ncbi.nlm.nih.gov/pubmed/30374016
http://dx.doi.org/10.1038/s41467-018-06714-z