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Maintenance of human haematopoietic stem and progenitor cells in vitro using a chemical cocktail

Identification of effective culture conditions to maintain and possibly expand human HSPCs in vitro is an important goal. Recent advances highlight the efficacy of chemicals in maintaining and converting cell fates. We screened 186 chemicals and found that a combination of CHIR-99021, Forskolin and...

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Detalles Bibliográficos
Autores principales: Jiang, Mengmeng, Chen, Haide, Lai, Shujing, Wang, Renying, Qiu, Yunfei, Ye, Fang, Fei, Lijiang, Sun, Huiyu, Xu, Yang, Jiang, Xinyi, Zhou, Ziming, Zhang, Tingyue, Li, Yanwei, Xie, Jin, Fang, Qun, Gale, Robert Peter, Han, Xiaoping, Huang, He, Guo, Guoji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206058/
https://www.ncbi.nlm.nih.gov/pubmed/30393564
http://dx.doi.org/10.1038/s41421-018-0059-5