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Maintenance of human haematopoietic stem and progenitor cells in vitro using a chemical cocktail
Identification of effective culture conditions to maintain and possibly expand human HSPCs in vitro is an important goal. Recent advances highlight the efficacy of chemicals in maintaining and converting cell fates. We screened 186 chemicals and found that a combination of CHIR-99021, Forskolin and...
Autores principales: | Jiang, Mengmeng, Chen, Haide, Lai, Shujing, Wang, Renying, Qiu, Yunfei, Ye, Fang, Fei, Lijiang, Sun, Huiyu, Xu, Yang, Jiang, Xinyi, Zhou, Ziming, Zhang, Tingyue, Li, Yanwei, Xie, Jin, Fang, Qun, Gale, Robert Peter, Han, Xiaoping, Huang, He, Guo, Guoji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206058/ https://www.ncbi.nlm.nih.gov/pubmed/30393564 http://dx.doi.org/10.1038/s41421-018-0059-5 |
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