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IgG Glyco-Engineering to Improve IVIg Potency

Intravenous immunoglobulins (IVIg) are used in the treatment of different autoimmune and inflammatory diseases, such as immune thrombocytopenia and hemolytic anemia. One of the modes of action of IVIg is preventing phagocytosis of autoantibody-opsonized blood cells by saturation of the Fc-gamma rece...

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Detalles Bibliográficos
Autores principales: Bruggeman, Christine W., Dekkers, Gillian, Visser, Remco, Goes, Naneth W. M., van den Berg, Timo K., Rispens, Theo, Vidarsson, Gestur, Kuijpers, Taco W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206079/
https://www.ncbi.nlm.nih.gov/pubmed/30405631
http://dx.doi.org/10.3389/fimmu.2018.02442