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Killer immunoglobulin-like receptor genotype did not correlate with response to anti-PD-1 antibody treatment in a Japanese cohort

Immune checkpoint blockade (ICB) induces a remarkable response in patients with certain cancers. However, the response rate is not yet satisfactory. Biomarkers that help physicians identify patients who would benefit from ICB need to be developed. Killer immunoglobulin-like receptors (KIRs) are a cl...

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Detalles Bibliográficos
Autores principales: Ishida, Yoshihiro, Nakashima, Chisa, Kojima, Hiroto, Tanaka, Hidenori, Fujimura, Taku, Matsushita, Shigeto, Yamamoto, Yuki, Yoshino, Koji, Fujisawa, Yasuhiro, Otsuka, Atsushi, Kabashima, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206129/
https://www.ncbi.nlm.nih.gov/pubmed/30374122
http://dx.doi.org/10.1038/s41598-018-34044-z