Biglycan Regulates MG63 Osteosarcoma Cell Growth Through a LPR6/β-Catenin/IGFR-IR Signaling Axis

Biglycan, a small leucine rich proteoglycan (SLRP), is an important participant in bone homeostasis and development as well as in bone pathology. In the present study biglycan was identified as a positive regulator of MG63 osteosarcoma cell growth (p ≤ 0.001). IGF-I was shown to increase biglycan ex...

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Detalles Bibliográficos
Autores principales: Aggelidakis, John, Berdiaki, Aikaterini, Nikitovic, Dragana, Papoutsidakis, Antonis, Papachristou, Dionysios J., Tsatsakis, Aristidis M., Tzanakakis, George N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206209/
https://www.ncbi.nlm.nih.gov/pubmed/30406034
http://dx.doi.org/10.3389/fonc.2018.00470

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206209/
https://www.ncbi.nlm.nih.gov/pubmed/30406034
http://dx.doi.org/10.3389/fonc.2018.00470

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