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Biglycan Regulates MG63 Osteosarcoma Cell Growth Through a LPR6/β-Catenin/IGFR-IR Signaling Axis
Biglycan, a small leucine rich proteoglycan (SLRP), is an important participant in bone homeostasis and development as well as in bone pathology. In the present study biglycan was identified as a positive regulator of MG63 osteosarcoma cell growth (p ≤ 0.001). IGF-I was shown to increase biglycan ex...
Autores principales: | Aggelidakis, John, Berdiaki, Aikaterini, Nikitovic, Dragana, Papoutsidakis, Antonis, Papachristou, Dionysios J., Tsatsakis, Aristidis M., Tzanakakis, George N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206209/ https://www.ncbi.nlm.nih.gov/pubmed/30406034 http://dx.doi.org/10.3389/fonc.2018.00470 |
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