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Immune Checkpoints and Innovative Therapies in Glioblastoma

Targeting the Immune Checkpoint molecules (ICs; CTLA-4, PD-1, PD-L1/2, and others) which provide inhibitory signals to T cells, dramatically improves survival in hard-to-treat tumors. The establishment of an immunosuppressive environment prevents endogenous immune response in glioblastoma; therefore...

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Detalles Bibliográficos
Autores principales: Romani, Massimo, Pistillo, Maria Pia, Carosio, Roberta, Morabito, Anna, Banelli, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206227/
https://www.ncbi.nlm.nih.gov/pubmed/30406030
http://dx.doi.org/10.3389/fonc.2018.00464