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Effects of food restriction on the expression of genes related to acetaminophen-induced liver toxicity in rats

It is well known that fasting substantially affects the metabolism of drugs and chemicals. Food restriction also affects drug kinetics, such as absorption, metabolism, and excretion, and therefore, it can potentially modulate the onset of chemical toxicity or drug-induced adverse reactions. In the p...

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Detalles Bibliográficos
Autores principales: Tsuchiya, Yuya, Sakai, Hiroki, Hirata, Akihiro, Yanai, Tokuma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society of Toxicologic Pathology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206280/
https://www.ncbi.nlm.nih.gov/pubmed/30393430
http://dx.doi.org/10.1293/tox.2018-0009