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Gastric Cancer Cell Lines Have Different MYC-Regulated Expression Patterns but Share a Common Core of Altered Genes

MYC is an oncogene responsible for excessive cell growth in cancer, enabling transcriptional activation of genes involved in cell cycle regulation, metabolism, and apoptosis, and is usually overexpressed in gastric cancer (GC). By using siRNA and Next-Generation Sequencing (NGS), we identified MYC-r...

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Detalles Bibliográficos
Autores principales: Maués, Jersey Heitor da S., Ribeiro, Helem Ferreira, Pinto, Giovanny R., Lopes, Luana de Oliveira, Lamarão, Letícia M., Pessoa, Carla Mariana F., Moreira-Nunes, Caroline de Fátima Aquino, de Carvalho, Raimundo Miranda, Assumpção, Paulo P., Rey, Juan A., Burbano, Rommel M. Rodríguez
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206580/
https://www.ncbi.nlm.nih.gov/pubmed/30410872
http://dx.doi.org/10.1155/2018/5804376