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Gastric Cancer Cell Lines Have Different MYC-Regulated Expression Patterns but Share a Common Core of Altered Genes
MYC is an oncogene responsible for excessive cell growth in cancer, enabling transcriptional activation of genes involved in cell cycle regulation, metabolism, and apoptosis, and is usually overexpressed in gastric cancer (GC). By using siRNA and Next-Generation Sequencing (NGS), we identified MYC-r...
Autores principales: | Maués, Jersey Heitor da S., Ribeiro, Helem Ferreira, Pinto, Giovanny R., Lopes, Luana de Oliveira, Lamarão, Letícia M., Pessoa, Carla Mariana F., Moreira-Nunes, Caroline de Fátima Aquino, de Carvalho, Raimundo Miranda, Assumpção, Paulo P., Rey, Juan A., Burbano, Rommel M. Rodríguez |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206580/ https://www.ncbi.nlm.nih.gov/pubmed/30410872 http://dx.doi.org/10.1155/2018/5804376 |
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