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Papain Ameliorates the MPAs Formation-Mediated Activation of Monocytes by Inhibiting Cox-2 Expression via Regulating the MAPKs and PI3K/Akt Signal Pathway

Monocytes activation and subsequent inflammatory response mediated by monocyte-platelet aggregates (MPAs) formation play the key roles in the early pathogenesis of atherosclerosis (AS). Exploration of novel drugs to ameliorate MPAs formation-mediated monocytes activation would be helpful for the tre...

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Detalles Bibliográficos
Autores principales: Fei, Xianming, Yuan, Wufeng, Zhao, Yan, Wang, Huan, Bai, Shi, Huang, Qinghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206584/
https://www.ncbi.nlm.nih.gov/pubmed/30410927
http://dx.doi.org/10.1155/2018/3632084