Epigenetics of Delirium and Aging: Potential Role of DNA Methylation Change on Cytokine Genes in Glia and Blood Along With Aging

Background: Delirium in elderly patients is common and dangerous. Major risk factors include aging and exogenous insults, such as infection or surgery. In animal models, aging enhances pro-inflammatory cytokine release from microglia in response to exogenous insults. The epigenetic mechanism DNA met...

Descripción completa

Detalles Bibliográficos
Autores principales: Shinozaki, Gen, Braun, Patricia R., Hing, Benjamin W. Q., Ratanatharathorn, Andrew, Klisares, Mason J., Duncan, Gabrielle N., Jellison, Sydney S., Heinzman, Jonathan T., Nagahama, Yasunori, Close, Liesl, Sabbagh, Sayeh, Dlouhy, Brian J., Howard, Matthew A., Kawasaki, Hiroto, Cho, Hyunkeun R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206747/
https://www.ncbi.nlm.nih.gov/pubmed/30405391
http://dx.doi.org/10.3389/fnagi.2018.00311

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206747/
https://www.ncbi.nlm.nih.gov/pubmed/30405391
http://dx.doi.org/10.3389/fnagi.2018.00311

Ejemplares similares