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A surface antigen of Orientia tsutsugamushi activates human monocyte-derived dendritic cells via nuclear factor-kB & p38 mitogen-activated protein kinase pathways

BACKGROUND & OBJECTIVES: Scrub typhus is a chigger-borne disease caused by Orientia tsutsugamushi. The immunological reactions to O. tsutsugamushi infection are not completely understood. In this study, we investigated the response of dendritic cells (DCs) to a major 56-kDa scrub typhus antigen...

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Detalles Bibliográficos
Autores principales: Jan, Rong-Hwa, Chen, Chia-Jung, Hong, Yi-Ren, Lin, Yu-Li, Chen, Li-Kuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206779/
https://www.ncbi.nlm.nih.gov/pubmed/30381545
http://dx.doi.org/10.4103/ijmr.IJMR_1417_16