Methylenetetrahydrofolate Dehydrogenase 1 Silencing Expedites the Apoptosis of Non-Small Cell Lung Cancer Cells via Modulating DNA Methylation

BACKGROUND: Non-small cell lung cancer (NSCLC) accounts for about 85% of all types of lung cancer. Methylenetetrahydrofolate dehydrogenase 1 (MTHFD1) is involved in DNA methylation, and DNA methylation is related to tumorigenesis. The role of MTHFD1 in NSCLC was examined in our study. MATERIAL/METHO...

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Detalles Bibliográficos
Autores principales: Ding, Ke, Jiang, Jianyang, Chen, Liang, Xu, Xiaohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2018
Materias:
Lab/In Vitro Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206813/
https://www.ncbi.nlm.nih.gov/pubmed/30343310
http://dx.doi.org/10.12659/MSM.910265

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206813/
https://www.ncbi.nlm.nih.gov/pubmed/30343310
http://dx.doi.org/10.12659/MSM.910265

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