Validation of differentially methylated microRNAs identified from an epigenome-wide association study; Sanger and next generation sequencing approaches

OBJECTIVES: Altered DNA methylation and microRNA profiles are associated with diabetic kidney disease. This study compared different sequencing approaches to define the genetic and epigenetic architecture of sequences surrounding microRNAs associated with diabetic kidney disease. RESULTS: We compare...

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Detalles Bibliográficos
Autores principales: Smyth, Laura J., Maxwell, Alexander P., Benson, Katherine A., Kilner, Jill, McKay, Gareth J., McKnight, Amy Jayne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206874/
https://www.ncbi.nlm.nih.gov/pubmed/30373632
http://dx.doi.org/10.1186/s13104-018-3872-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206874/
https://www.ncbi.nlm.nih.gov/pubmed/30373632
http://dx.doi.org/10.1186/s13104-018-3872-x

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