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Validation of differentially methylated microRNAs identified from an epigenome-wide association study; Sanger and next generation sequencing approaches
OBJECTIVES: Altered DNA methylation and microRNA profiles are associated with diabetic kidney disease. This study compared different sequencing approaches to define the genetic and epigenetic architecture of sequences surrounding microRNAs associated with diabetic kidney disease. RESULTS: We compare...
Autores principales: | Smyth, Laura J., Maxwell, Alexander P., Benson, Katherine A., Kilner, Jill, McKay, Gareth J., McKnight, Amy Jayne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206874/ https://www.ncbi.nlm.nih.gov/pubmed/30373632 http://dx.doi.org/10.1186/s13104-018-3872-x |
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