Sphingosine Kinase Activates the Mitochondrial Unfolded Protein Response and Is Targeted to Mitochondria by Stress

The mitochondrial unfolded protein response (UPR(mt)) is critical for maintaining mitochondrial protein homeostasis in response to mitochondrial stress, but early steps in UPR(mt) activation are not well understood. Here, we report a function for SPHK-1 sphingosine kinase in activating the UPR(mt) i...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Sungjin, Sieburth, Derek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206875/
https://www.ncbi.nlm.nih.gov/pubmed/30208318
http://dx.doi.org/10.1016/j.celrep.2018.08.037

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206875/
https://www.ncbi.nlm.nih.gov/pubmed/30208318
http://dx.doi.org/10.1016/j.celrep.2018.08.037

Ejemplares similares