Cargando…
Sphingosine Kinase Activates the Mitochondrial Unfolded Protein Response and Is Targeted to Mitochondria by Stress
The mitochondrial unfolded protein response (UPR(mt)) is critical for maintaining mitochondrial protein homeostasis in response to mitochondrial stress, but early steps in UPR(mt) activation are not well understood. Here, we report a function for SPHK-1 sphingosine kinase in activating the UPR(mt) i...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2018
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206875/ https://www.ncbi.nlm.nih.gov/pubmed/30208318 http://dx.doi.org/10.1016/j.celrep.2018.08.037 |