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Sirolimus is efficacious in treatment for extensive and/or complex slow-flow vascular malformations: a monocentric prospective phase II study

BACKGROUND: Extensive and complex vascular malformations often cause chronic pain and severe functional restraint. Conventional treatments, such as surgery and/or sclerotherapy, are rarely curative, underscoring the great need for new therapeutic modalities. Recent preclinical and clinical data demo...

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Detalles Bibliográficos
Autores principales: Hammer, Jennifer, Seront, Emmanuel, Duez, Steven, Dupont, Sophie, Van Damme, An, Schmitz, Sandra, Hoyoux, Claire, Chopinet, Caroline, Clapuyt, Philippe, Hammer, Frank, Vikkula, Miikka, Boon, Laurence M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206885/
https://www.ncbi.nlm.nih.gov/pubmed/30373605
http://dx.doi.org/10.1186/s13023-018-0934-z