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Sirolimus is efficacious in treatment for extensive and/or complex slow-flow vascular malformations: a monocentric prospective phase II study
BACKGROUND: Extensive and complex vascular malformations often cause chronic pain and severe functional restraint. Conventional treatments, such as surgery and/or sclerotherapy, are rarely curative, underscoring the great need for new therapeutic modalities. Recent preclinical and clinical data demo...
Autores principales: | Hammer, Jennifer, Seront, Emmanuel, Duez, Steven, Dupont, Sophie, Van Damme, An, Schmitz, Sandra, Hoyoux, Claire, Chopinet, Caroline, Clapuyt, Philippe, Hammer, Frank, Vikkula, Miikka, Boon, Laurence M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206885/ https://www.ncbi.nlm.nih.gov/pubmed/30373605 http://dx.doi.org/10.1186/s13023-018-0934-z |
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