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Thiopurine metabolite level and toxicity in Indians with inflammatory bowel disease

BACKGROUND AND AIM: A lower dose requirement and higher toxicity of thiopurine is reported in Asian patients with inflammatory bowel disease (IBD) as compared with Caucasian patients. These reports are based on thiopurine methyltransferase measurement studies rather than metabolite estimation. We st...

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Detalles Bibliográficos
Autores principales: Parkar, Suruchi P, Dherai, Alpa J, Desai, Devendra C, Ashavaid, Tester F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Publishing Asia Pty Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206977/
https://www.ncbi.nlm.nih.gov/pubmed/30483529
http://dx.doi.org/10.1002/jgh3.12004