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Non-small cell to small cell lung cancer on PD-1 inhibitors: two cases on potential histologic transformation
INTRODUCTION: Histologic transformation from non-small cell lung cancer (NSCLC) to small cell lung cancer (SCLC) is a well-recognized mechanism of resistance in EGFR-mutant adenocarcinoma upon treatment with TKIs, but rarely reported with programmed death1 (PD-1) inhibitors. We report two cases of p...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6207227/ https://www.ncbi.nlm.nih.gov/pubmed/30498383 http://dx.doi.org/10.2147/LCTT.S173724 |