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Virus and CTL dynamics in the extrafollicular and follicular tissue compartments in SIV-infected macaques

Data from SIV-infected macaques indicate that virus-specific cytotoxic T lymphocytes (CTL) are mostly present in the extrafollicular (EF) compartment of the lymphoid tissue, with reduced homing to the follicular (F) site. This contributes to the majority of the virus being present in the follicle an...

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Detalles Bibliográficos
Autores principales: Wodarz, Dominik, Skinner, Pamela J., Levy, David N., Connick, Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6207320/
https://www.ncbi.nlm.nih.gov/pubmed/30335747
http://dx.doi.org/10.1371/journal.pcbi.1006461