Cargando…
Virus and CTL dynamics in the extrafollicular and follicular tissue compartments in SIV-infected macaques
Data from SIV-infected macaques indicate that virus-specific cytotoxic T lymphocytes (CTL) are mostly present in the extrafollicular (EF) compartment of the lymphoid tissue, with reduced homing to the follicular (F) site. This contributes to the majority of the virus being present in the follicle an...
Autores principales: | Wodarz, Dominik, Skinner, Pamela J., Levy, David N., Connick, Elizabeth |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6207320/ https://www.ncbi.nlm.nih.gov/pubmed/30335747 http://dx.doi.org/10.1371/journal.pcbi.1006461 |
Ejemplares similares
-
Follicular regulatory T cells impair follicular T helper cells in HIV and SIV infection
por: Miles, Brodie, et al.
Publicado: (2015) -
Follicular Regulatory CD8 T Cells Impair the Germinal Center Response in SIV and Ex Vivo HIV Infection
por: Miles, Brodie, et al.
Publicado: (2016) -
CTL Escape and Viral Fitness in HIV/SIV Infection
por: Seki, Sayuri, et al.
Publicado: (2012) -
Simian Immunodeficiency Virus (SIV)-Specific Chimeric Antigen Receptor-T Cells Engineered to Target B Cell Follicles and Suppress SIV Replication
por: Haran, Kumudhini Preethi, et al.
Publicado: (2018) -
Viral Superantigen Drives Extrafollicular and Follicular B Cell Differentiation Leading to Virus-specific Antibody Production
por: Luther, Sanjiv A., et al.
Publicado: (1997)