Cargando…

A central role for PBP2 in the activation of peptidoglycan polymerization by the bacterial cell elongation machinery

Cell elongation in rod-shaped bacteria is mediated by the Rod system, a conserved morphogenic complex that spatially controls cell wall assembly by the glycan polymerase RodA and crosslinking enzyme PBP2. Using Escherichia coli as a model system, we identified a PBP2 variant that promotes Rod system...

Descripción completa

Detalles Bibliográficos
Autores principales: Rohs, Patricia D. A., Buss, Jackson, Sim, Sue I., Squyres, Georgia R., Srisuknimit, Veerasak, Smith, Mandy, Cho, Hongbaek, Sjodt, Megan, Kruse, Andrew C., Garner, Ethan C., Walker, Suzanne, Kahne, Daniel E., Bernhardt, Thomas G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6207328/
https://www.ncbi.nlm.nih.gov/pubmed/30335755
http://dx.doi.org/10.1371/journal.pgen.1007726