Altered bone growth dynamics prefigure craniosynostosis in a zebrafish model of Saethre-Chotzen syndrome

Cranial sutures separate the skull bones and house stem cells for bone growth and repair. In Saethre-Chotzen syndrome, mutations in TCF12 or TWIST1 ablate a specific suture, the coronal. This suture forms at a neural-crest/mesoderm interface in mammals and a mesoderm/mesoderm interface in zebrafish....

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Detalles Bibliográficos
Autores principales: Teng, Camilla S, Ting, Man-chun, Farmer, D'Juan T, Brockop, Mia, Maxson, Robert E, Crump, J Gage
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6207424/
https://www.ncbi.nlm.nih.gov/pubmed/30375332
http://dx.doi.org/10.7554/eLife.37024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6207424/
https://www.ncbi.nlm.nih.gov/pubmed/30375332
http://dx.doi.org/10.7554/eLife.37024

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