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Altered bone growth dynamics prefigure craniosynostosis in a zebrafish model of Saethre-Chotzen syndrome
Cranial sutures separate the skull bones and house stem cells for bone growth and repair. In Saethre-Chotzen syndrome, mutations in TCF12 or TWIST1 ablate a specific suture, the coronal. This suture forms at a neural-crest/mesoderm interface in mammals and a mesoderm/mesoderm interface in zebrafish....
Autores principales: | Teng, Camilla S, Ting, Man-chun, Farmer, D'Juan T, Brockop, Mia, Maxson, Robert E, Crump, J Gage |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6207424/ https://www.ncbi.nlm.nih.gov/pubmed/30375332 http://dx.doi.org/10.7554/eLife.37024 |
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