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Organisms with alternative genetic codes resolve unassigned codons via mistranslation and ribosomal rescue

Organisms possessing genetic codes with unassigned codons raise the question of how cellular machinery resolves such codons and how this could impact horizontal gene transfer. Here, we use a genomically recoded Escherichia coli to examine how organisms address translation at unassigned UAG codons, w...

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Detalles Bibliográficos
Autores principales: Ma, Natalie Jing, Hemez, Colin F, Barber, Karl W, Rinehart, Jesse, Isaacs, Farren J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6207430/
https://www.ncbi.nlm.nih.gov/pubmed/30375330
http://dx.doi.org/10.7554/eLife.34878