Cargando…

Retromer in Synaptic Function and Pathology

The retromer complex mediates export of select transmembrane proteins from endosomes to the trans-Golgi network (TGN) or to the plasma membrane. Dysfunction of retromer has been linked with slowly progressing neurodegenerative disorders, including Alzheimer’s and Parkinson’s disease (AD and PD). As...

Descripción completa

Detalles Bibliográficos
Autores principales: Brodin, Lennart, Shupliakov, Oleg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6207580/
https://www.ncbi.nlm.nih.gov/pubmed/30405388
http://dx.doi.org/10.3389/fnsyn.2018.00037