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The Prospects of an Active Vaccine Against Asthma Targeting IL-5

Allergen-specific T helper type 2 (Th2) responses followed by eosinophilic inflammation of the lung are important causes of allergic asthma. Interleukin-5 (IL-5) is a master regulator of eosinophil differentiation as well as activation. Blocking IL-5 using monoclonal antibodies (mAbs) against IL-5 i...

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Detalles Bibliográficos
Autores principales: Bachmann, Martin F., El-Turabi, Aadil, Fettelschoss-Gabriel, Antonia, Vogel, Monique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6207595/
https://www.ncbi.nlm.nih.gov/pubmed/30405579
http://dx.doi.org/10.3389/fmicb.2018.02522