MicroRNA-122 Mimic Improves Stroke Outcomes and Indirectly Inhibits NOS2 After Middle Cerebral Artery Occlusion in Rats

Aim: Our previous study demonstrated miR-122 mimic decreased NOS2 expression in blood leucocytes and improved stroke outcomes when given immediately after middle cerebral artery occlusion (MCAO) in rats. Since NOS2 is associated with neuro-inflammation in stroke and decreasing NOS2 expression alone...

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Detalles Bibliográficos
Autores principales: Lv, Bo, Cheng, Xiyuan, Sharp, Frank R., Ander, Bradley P., Liu, Da Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6207613/
https://www.ncbi.nlm.nih.gov/pubmed/30405345
http://dx.doi.org/10.3389/fnins.2018.00767

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6207613/
https://www.ncbi.nlm.nih.gov/pubmed/30405345
http://dx.doi.org/10.3389/fnins.2018.00767

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