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Direct cysteine sulfenylation drives activation of the Src kinase

The Src kinase controls aspects of cell biology and its activity is regulated by intramolecular structural changes induced by protein interactions and tyrosine phosphorylation. Recent studies indicate that Src is additionally regulated by redox-dependent mechanisms, involving oxidative modification(...

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Detalles Bibliográficos
Autores principales: Heppner, David E., Dustin, Christopher M., Liao, Chenyi, Hristova, Milena, Veith, Carmen, Little, Andrew C., Ahlers, Bethany A., White, Sheryl L., Deng, Bin, Lam, Ying-Wai, Li, Jianing, van der Vliet, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6207713/
https://www.ncbi.nlm.nih.gov/pubmed/30375386
http://dx.doi.org/10.1038/s41467-018-06790-1