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Quantitative evaluation of incomplete preweaning lethality in mice by using the CRISPR/Cas9 system

Various molecular biology techniques implementing genome editing have made it possible to generate mouse mutants for nearly all known genes; as a result, the International Mouse Phenotyping Consortium (IMPC) database listing the phenotypes of genetically modified mice has been established. Among mou...

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Detalles Bibliográficos
Autores principales: Nakamura, Takumi, Nakajima, Kazuo, Ohnishi, Tetsuo, Yoshikawa, Takeo, Nakanishi, Moe, Takumi, Toru, Tsuboi, Takashi, Kato, Tadafumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6207718/
https://www.ncbi.nlm.nih.gov/pubmed/30375401
http://dx.doi.org/10.1038/s41598-018-34270-5