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Adrenal hormones mediate disease tolerance in malaria

Malaria reduces host fitness and survival by pathogen-mediated damage and inflammation. Disease tolerance mechanisms counter these negative effects without decreasing pathogen load. Here, we demonstrate that in four different mouse models of malaria, adrenal hormones confer disease tolerance and pro...

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Detalles Bibliográficos
Autores principales: Vandermosten, Leen, Pham, Thao-Thy, Knoops, Sofie, De Geest, Charlotte, Lays, Natacha, Van der Molen, Kristof, Kenyon, Christopher J., Verma, Manu, Chapman, Karen E., Schuit, Frans, De Bosscher, Karolien, Opdenakker, Ghislain, Van den Steen, Philippe E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6207723/
https://www.ncbi.nlm.nih.gov/pubmed/30375380
http://dx.doi.org/10.1038/s41467-018-06986-5