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Adrenal hormones mediate disease tolerance in malaria
Malaria reduces host fitness and survival by pathogen-mediated damage and inflammation. Disease tolerance mechanisms counter these negative effects without decreasing pathogen load. Here, we demonstrate that in four different mouse models of malaria, adrenal hormones confer disease tolerance and pro...
Autores principales: | Vandermosten, Leen, Pham, Thao-Thy, Knoops, Sofie, De Geest, Charlotte, Lays, Natacha, Van der Molen, Kristof, Kenyon, Christopher J., Verma, Manu, Chapman, Karen E., Schuit, Frans, De Bosscher, Karolien, Opdenakker, Ghislain, Van den Steen, Philippe E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6207723/ https://www.ncbi.nlm.nih.gov/pubmed/30375380 http://dx.doi.org/10.1038/s41467-018-06986-5 |
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