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Chemically monoubiquitinated PEX5 binds to the components of the peroxisomal docking and export machinery

Peroxisomal matrix proteins contain either a peroxisomal targeting sequence 1 (PTS1) or a PTS2 that are recognized by the import receptors PEX5 and PEX7, respectively. PEX5 transports the PTS1 proteins and the PEX7/PTS2 complex to the docking translocation module (DTM) at the peroxisomal membrane. A...

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Detalles Bibliográficos
Autores principales: Hagmann, Vera, Sommer, Stefanie, Fabian, Patrick, Bierlmeier, Jan, van Treel, Nadine, Mootz, Henning D., Schwarzer, Dirk, Azevedo, Jorge E., Dodt, Gabriele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6207756/
https://www.ncbi.nlm.nih.gov/pubmed/30375424
http://dx.doi.org/10.1038/s41598-018-34200-5