Network integration of multi-tumour omics data suggests novel targeting strategies

We characterize different tumour types in search for multi-tumour drug targets, in particular aiming for drug repurposing and novel drug combinations. Starting from 11 tumour types from The Cancer Genome Atlas, we obtain three clusters based on transcriptomic correlation profiles. A network-based an...

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Detalles Bibliográficos
Autores principales: do Valle, Ítalo Faria, Menichetti, Giulia, Simonetti, Giorgia, Bruno, Samantha, Zironi, Isabella, Durso, Danielle Fernandes, Mombach, José C. M., Martinelli, Giovanni, Castellani, Gastone, Remondini, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6207774/
https://www.ncbi.nlm.nih.gov/pubmed/30375513
http://dx.doi.org/10.1038/s41467-018-06992-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6207774/
https://www.ncbi.nlm.nih.gov/pubmed/30375513
http://dx.doi.org/10.1038/s41467-018-06992-7

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