Molecular weight of surface immobilized hyaluronic acid influences CD44-mediated binding of gastric cancer cells

The physiological importance of the interactions between hyaluronic acid (HA) and its main membrane receptor, CD44, in pathological processes, e.g. cancer, is well recognized. However, these interactions are mainly studied in solution, whereas HA in the extracellular matrix (ECM) is partially immobi...

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Detalles Bibliográficos
Autores principales: Amorim, Sara, da Costa, Diana Soares, Freitas, Daniela, Reis, Celso A., Reis, Rui L., Pashkuleva, Iva, Pires, Ricardo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6207784/
https://www.ncbi.nlm.nih.gov/pubmed/30375477
http://dx.doi.org/10.1038/s41598-018-34445-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6207784/
https://www.ncbi.nlm.nih.gov/pubmed/30375477
http://dx.doi.org/10.1038/s41598-018-34445-0

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