A Rare Case of Heterozygous Gain of Function Thyrotropin Receptor Mutation Associated with Development of Thyroid Follicular Carcinoma

Activating mutations in thyrotropin receptor (TSHR) have been previously described in the context of nonautoimmune hyperthyroidism and thyroid adenomas. We describe, for the first time, a mutation in TSHR contributing to follicular thyroid carcinoma (FTC) in an adolescent. A 12-year-old girl present...

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Detalles Bibliográficos
Autores principales: Blackburn, James, Giri, Dinesh, Ciolka, Barbara, Gossan, Nicole, Didi, Mohammad, Kokai, George, Waghorn, Alison, Jones, Matthew, Senniappan, Senthil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6207865/
https://www.ncbi.nlm.nih.gov/pubmed/30416831
http://dx.doi.org/10.1155/2018/1381730

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6207865/
https://www.ncbi.nlm.nih.gov/pubmed/30416831
http://dx.doi.org/10.1155/2018/1381730

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