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Structure-based assessment and network analysis of targeting 14-3-3 proteins in prostate cancer
Developing combination therapy for castrate-resistant prostate cancer (CRPC) may require exploiting new drug targets outside androgen receptor and PI3K / AKT / mTOR signal transduction pathways implicated in prostate cancer (PCa) progression. One such possible new target is YWHAZ of the 14-3-3 prote...
Autores principales: | Root, Alex, Beizaei, Azadeh, Ebhardt, H. Alexander |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208026/ https://www.ncbi.nlm.nih.gov/pubmed/30382885 http://dx.doi.org/10.1186/s12943-018-0905-y |
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